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Leukemia cell infiltration causes defective erythropoiesis partially through MIP-1α/CCL3.
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Loss of Dnmt3b accelerates MLL-AF9 leukemia progression.
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Novel regulators in hematopoietic stem cells can be revealed by a functional approach under leukemic condition.
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Distinct molecular abnormalities underlie unique clinical features of essential thrombocythemia in children.
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2016, 30(3):746-9
Rictor Plays a Pivotal Role in Maintaining Quiescence as well as Stemness of Leukemia Stem Cells in MLL-Driven Leukemia.
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The catalytic activity of TET2 is essential for its myeloid malignancy-suppressive function in hematopoietic stem/progenitor cells.
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Epigenetic silencing of miR-137 induces drug resistance and chromosomal instability by targeting AURKA in multiple myeloma.
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Thrombopoietin receptor agonists shift the balance of Fcγ receptors towards inhibitory receptor IIb on monocytes in ITP.
Blood.
2016 Aug 11;128(6):852-61.
Osteoclasts promote immune suppressive microenvironment in multiple myeloma: therapeutic implication.
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Enhanced Generation of Integration-free iPSCs from Human Adult Peripheral Blood Mononuclear Cells with an Optimal Combination of Episomal Vectors.
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Rheb1 promotes tumor progression through mTORC1 in MLL-AF9-initiated murine acute myeloid leukemia.
Journal of Hematology and Oncology.
2016. Apr 12; 9:36. DOI: 10.1186/s13045-016-0264-3
Microarray-based analysis and clinical validation identify ubiquitin-conjugating enzyme E2E1 (UBE2E1) as a prognostic factor in acute myeloid leukemia.
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Antifungal prophylaxis of patients undergoing allogenetic hematopoietic stem cell transplantation in China: a multicenter prospective observational study.
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2016 Sep 23;9(1): 97.
Chasing the precursor of functional hematopoietic stem cells at the single cell levels in mouse embryos.
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2016 Jul 22;9(1):58.
Alantolactone selectively ablates acute myeloid leukemia stem and progenitor cells.
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2016 Sep 22;9(1):93.
Mesenchymal stem cells deliver and release conditionally replicative adenovirus depending on hepatic differentiation to eliminate hepatocellular carcinoma cells specifically
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Rac1 GTPase promotes interaction of hematopoietic stem/progenitor cell with niche and participates in leukemia initiation and maintenance in mouse.
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An analysis by the MPN QOL International Study Group.
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Multicentre, randomised phase III study of the efficacy andsafety of eltrombopag in Chinese patients with chronicimmune thrombocytopenia.
Br J Haematol.
2016 Oct 13. doi: 10.1111/bjh.14380.
Validation of the WHO 2016 proposals for Myelodysplastic syndromes patients with the presence of ring sideroblasts but without excess blasts.
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ASXL1 plays an important role in erythropoiesis
Scientific Reports
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Different Effects of sgRNA Length on CRISPR-mediated Gene Knockout Efficiency.
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Bone Marrow Is a Reservoir for Cardiac Resident Stem Cells.
Sci Rep.
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Knock-down of CIAPIN1 sensitizes K562 chronic myeloid leukemia cells to imatinib by regulation of cell cycle and apoptosis-associated members via NF-κB and ERK5 signaling pathway.
Biochemical Pharmacology.
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Upregulation of miR-99a is associated with poor prognosis of acute myeloid leukemia and promotes myeloid leukemia cell expansion
Oncotarget
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A molecular pathology method for sequential fluorescence in situ hybridization for multi-gene analysis at the single-cell level.
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2016 Jun 23.doi: 10.18632/oncotarget.10245.
Construction of a new anti-CD19 chimeric antigen receptor and the anti-leukemia function study of the transduced T cells
Oncotarget,
2016, 7(9):10638-49
Multiplex ligation-dependent probe amplification assay identifies additional copy number changes compared with R-band karyotype and provide more accuracy prognostic information in myelodysplastic syndromes.
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Elevated neutrophil-to-lymphocyte ratio and monocyte-to-lymphocyte ratio and decreased platelet-to-lymphocyte ratio are associated with poor prognosis in multiple myeloma.
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Serum high expression of miR-214 and miR-135b as novel predictor for myeloma bone disease development and prognosis.
Oncotarget.
2016 Apr 12;7(15):19589-600.
Mutations or copy number losses of CD58 and TP53 genes in diffuse large B cell lymphoma are independent unfavorable prognostic factors.
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Antineoplastic effects and mechanisms of micheliolide in acute myelogenous leukemia stem cells.
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E1A-engineered human umbilical cord mesenchymal stem cells as carriers and amplifiers for adenovirus suppress hepatocarcinoma in mice
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2016 Aug 9;7(32): 51815-51828.
The different prognostic impact of type-1 or type-1 like and type-2 or type-2 like CALR mutations in patients with primary myelofibrosis.
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Heterogeneity of proangiogenic features in mesenchymal stem cells derived from bone marrow, adipose tissue, umbilical cord, and placenta.
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VCAM-1+ placenta chorionic villi-derived mesenchymal stem cells display potent pro-angiogenic activity.
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Reprogramming of Notch1-induced acute lymphoblastic leukemia cells into pluripotent stem cells in mice.
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Bone marrow fibrosis grade is an independent risk factor for overall survival in patients with primary myelofibrosis.
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Integrated Biophysical and Biochemical Signals Augment Megakaryopoiesis and Thrombopoiesis in a Three-Dimensional Rotary Culture System.
Stem Cells Transl Med，
2016，5（2）：175-185。
Mesenchymal Stem Cells Derived from Human Bone Marrow and Adipose Tissue Maintain Their Immunosuppressive Properties After Chondrogenic Differentiation: Role of HLA-G.
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2016 Oct 1;25(19):1454-69.
StemCellCKB: An Integrated Stem Cell-Specific Chemogenomics KnowledgeBase for Target Identification and Systems-Pharmacology Research.
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Mol Immunol.
2016 Oct;78:89-97.
'Waterloo': when normal blood cells meet leukemia.
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Prediction of adeno-associated virus neutralizing antibody activity for clinical application.
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Stromal cell-derived factor-1 rs2297630 polymorphism associated with platelet production and treatment response in Chinese patients with chronic immune thrombocytopenia.
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2016 Jun;27(4):338-43. (IF: 2.982)
The polymorphisms of tumor necrosis factor-induced protein 3 gene may contribute to the susceptibility of chronic primary immune thrombocytopenia in Chinese population.
Platelet.
2016, 27(1):26-31 (IF: 2.982)
Impaired Autophagy in Adult Bone Marrow CD34+ Cells of Patients with Aplastic Anemia: Possible Pathogenic Significance.
PLoS One.
2016 Mar 1; 11(3):e0149586.
PD-1 Antibody Monotherapy for Malignant Melanoma: A Systematic Review and Meta-Analysis.
PLoS One.
2016 Aug 2;11(8): e0160485.
Clinical profile of megaloblastic anemia in China: a single center experience from MegA-1710 program over two decades.
Ann Hematol.
2016 Apr; 95(5):827-8.
SIRT2 mediates multidrug resistance in acute myelogenous leukemia cells via ERK1/2 signaling pathway.
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Persistent elevated bone marrow plasma levels of thrombopoietin in patients with aplastic anemia.
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Effects of the multidrug resistance-1 gene on drug resistance in primary immune thrombocytopenia.
Autoimmunity.
2016,49(7):486-495
Aberrant expression of long noncoding RNA TMEVPG1 in patients with primary immune thrombocytopenia
Autoimmunity.
2016,49(7):496-502
Different dosages of intravenous immunoglobulin (IVIg) in treating immune thrombocytopenia with long-term follow-up of three years: Results of a prospective study including 167 cases.
Autoimmunity.
2016 Feb;49(1):50-7 (IF: 2.714)
Abnormal lipid rafts related ganglioside expression and signaling in T lymphocytes in immune thrombocytopenia patients.
Autoimmunity.
2016 Feb;49(1):58-68(IF: 2.714)
Tri-allelic patterns at the D7S820 locus detected in twogenerations of a Chinese family.，
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Transcriptome AnalysisReveals a Ribosome Constituents Disorder Involved in the RPL5 DownregulatedZebrafish Model of Diamond-Blackfan Anemia.
BMC Medical Genomics.
2016 Mar 9;9(1):13. doi: 10.1186/s12920-016-0174-9.
Identification of mutations in the F8 and F9 gene in families with haemophilia using targeted high-throughput sequencing.
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Chinese HERO study group. The demographics, treatment characteristics and quality of life of adult people with haemophilia in China - results from the HERO study.
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Sam68 affects cell proliferation and apoptosis of human adult T-acute lymphoblastic leukemia cells via AKT/mTOR signal pathway.
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Correlation of Tc17 cells at early stages after allogeneic hematopoietic stem cell transplantation with acute graft-versus-host disease.
Int Immunopharmacol.
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Long-term results of splenectomy in adult chronic immune thrombocytopenia.
Eur J Haematol.
2016 Oct 18. doi: 10.1111/ejh.12821.
Decreased expression of vitamin D receptor may contribute to the hyperimmune status of patients with acquired aplastic anemia.
Eur J Haematol.
2016 May; 96(5):507-16.
Role of vitamin D receptor gene polymorphisms in aplastic anemia: a case-control study from China.
Int J Lab Hematol.
2016 Jun; 38(3):273-83.
A novel lymphoid progenitor cell population (LSKlow) is restricted by p18INK4c.
Exp Hematol.
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A new HLA-B allele, B*52:44, sequenced in a Chinese individual.
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2016 Jun;87(6):464-5.
Identi_cation of a novel HLA-C06variant allele HLA-C06166 by sequence-based typing ina Chineseindividual
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2016 Dec;88(6):315-316.
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Novel chemical attempts at ex vivo hematopoietic stem cell expansion.
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Interferon‑γ alters the microRNA profile of umbilical cord‑derived mesenchymal stem cells.
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TET2 mutations were predictive of inferior prognosis in the presence of ASXL1 mutations in patients with chronic myelomonocytic leukemia.
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Impact of Autologous Mesenchymal Stem Cell Infusion on NeuromyelitisOptica Spectrum Disorder: A Pilot, 2-Year Observational Study. CNS
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Fluorescence In situ Hybridization: Cell-Based Genetic Diagnostic and Research Applications.
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