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State Key Laboratory of Experimental Hematology

The State Key Laboratory of Experimental Hematology (SKLEH) was located in Institute of Hematology (IH) and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS&PUMC). It was established in 1988 by the support of Ministry of Science and Technology of People’s Republic of China. It was open to domestic and international collaboration in 1991 after being evaluated by Chinese government. It is the unique national laboratory engaged in basic and applied research of experimental hematology. The main aspects of research are: (1) Study of hematopoietic stem cell biology and plasticity; (2) Basic and applied study of hematopoiesis regulation and angiogenesis regulators; (3) Study on development of normal and abnormal hematopoietic cells and immunocytes, especially the mechanisms, diagnosis and treatment of hematological malignancy;(4) Biotechnology and Biotherapy; (5) Cell and molecular biology, pathophysiology. There set up four major technology platforms: the GMP pilot-scale production technology of genetic engineering drugs, stem cell banking technology, the antibody preparation technology and the high through-put screening of drug technology.

There are 13 professors, 7 associate professors, 8 mentors for doctoral degree and 10 for master degree, about 100 doctoral and master degree students under study. There are 2 professors awarded Cheung Kong Scholars, and 2 recipients of National Outstanding Young Foundation.

There were about 130 research projects carried on in SKLEH, including 4 National Key Technologies R&D Programs during the 9th Five-Year Plan Period, 3 National High Technology Research and Development Program (863 programs), 1 of National Climb Plan, 3 of National Outstanding Young Foundations and other 126 funds.

The SKLEH has won 1 national and 26 ministerial scientific prize. There were 47 books and 772 scientific articles published, of them 196 were SCI cited. The SKLEH also obtained 18 domestic patents.117 doctoral students and 99 master’s degree students graduated from the SKLEH.

The establishment of SKLEH provides an important base for the study of experimental hematology, education of students and scientific stuffs and academic exchanges. In the last few years the SKLEH held 4 international conferences: the 1st to the 3rd International Symposium of Hematopoiesis and Angiogenesis, and the First International Symposium on Engineering Antibody.

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