Prof. Zheng graduated from Peking University and got bachelor’s degree in 1990. He graduated from Peking Union Medical College and got master and Ph.D degree in 1993 and 1999. He acted as a visiting scholar in Kumamoto University for one year since 2005. He has been engaged in research in cell biology and molecular biology in the hematopoietic system focusing on the mechanism of intrinsic and microenvironmental on the genesis and progression of hematologic malignancies. He has obtained 10 grants from the National Natural Science Foundation, 2 key projects in basic research from the Tianjin Natural Science Foundation, 2 grants from Tianjin Natural Science Foundation. He also participated in scores of national, provincial and ministerial scientific research projects. He has published over one hundred research papers, among which 69 papers were published in SCI journals. As first author or corresponding author, he has published 65 papers (including 36 SCI paper) in domestic and international journals including J Hematol Oncol, Cancer Res, Haematologica、Cancer Lett、Cell Death Dis、Oncogene、Oncoimmunology、Stem Cell Res Ther, etc. He gained the Second Prize for Scientific and Technological Progress of the Ministry of Health in 1995, the Second Prize of Chinese Medical Award in 2002, the Second Prize of Tianjin Natural Science in 2005, the First Prize of Tianjin Natural Science in 2015, Second Prize in Natural Sciences of Excellent Achievements in Scientific Research of Higher Education Institutions. He was selected in the New Century Excellent Talents Support Program of the Ministry of Education in 2008 and honored as Excellent Teacher at Peking Union Medical College in 2011.
Ph.D, Cell Biology, Peking Union Medical College, Beijing, China, 1996-1999
MS, Cell Biology, Peking Union Medical College, Beijing, China, 1990-1993
BS, Biophysics, Peking University, Beijing, China, 1986-1990
Professor of Cell Biology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 2007-
Associate Professor of Cell Biology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 2000-2007
Assistant Professor of Cell Biology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 1995-2000
PRINCIPAL HONORS, AWARDS:
2016 Second Prize in Natural Sciences of Excellent Achievements in Scientific Research of Higher Education Institutions
2015 First Prize of Tianjin Natural Science
2008 New Century Excellent Talents Program of the Ministry of Education
2005 Second Prize of Tianjin Natural Science
2002 Second Prize of Chinese Medical Award
MAJOR NATIONAL LEADERSHIP POSITIONS, SOCIETIES AND BOARDS:
2024-2028 Member, 9th Council of the Chinese Society of Immunology
2025-2029 Executive Committee Member, 7th Medical Cell Biology Branch Committee of the Chinese Medical Association
2023-2028 Vice Chairman, 3rd Council of Tianjin Immunological Society
SELECTED PUBLICATIONS:
1. Yang FF, Feng WL, Wang H, Wang LN, Liu XL, Wang R, Chen C, Yang X, Zhang DY, Ren Q and Zheng GG*. Monocyte-derived leukemia-associated macrophages facilitate the extramedullary distribution of T-cell acute lymphoblastic leukemia cells. Cancer Res. 2020; 80 3677-91.
2. Feng WL#, Yang X#, Wang LN, Wang R, Yang FF, Wang H, Liu XL, Ren Q, Zhang YC, Zhu XF and Zheng GG*. P2X7 promotes the progression of MLL-AF9 induced acute myeloid leukemia by upregulation of Pbx3. Haematologica. 2021; 106 1278-89.
3. Wang R, Feng WL, Wang H, Wang LN, Yang X, Yang FF, Zhang YC, Liu XL, Zhang DY, Ren Q, Feng XM and Zheng GG*. Blocking migration of regulatory T cells to leukemic hematopoietic microenvironment delays disease progression in mouse leukemia model. Cancer Lett. 2020; 469 151-61.
4. Wang H, Zhang DY, Cui XX, Dai YB, Wang CC, Feng WL, Lv XQ, Li YF, Wang LN, Ru YX, Zhang YC, Ren Q and Zheng GG*. Loss of IRF7 accelerates acute myeloid leukemia progression and induces VCAM1-VLA-4 mediated intracerebral invasion. Oncogene. 2022; 41 2303-14.
5. Zhang DY, Cui XX, Li YF, Wang R, Wang H, Dai YB, Ren Q, Wang LN and Zheng GG*. Sox13 and M2-like leukemia-associated macrophages contribute to endogenous IL-34 caused accelerated progression of acute myeloid leukemia. Cell Death Dis. 2023;14 308