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Jiapei Yuan
PI, National Key Laboratory of Blood Science
Jiapei Yuan is a Research Fellow and Tenure-Track Assistant Professor at Peking Union Medical College. Her research focuses on 3D genomics and precision oncology, with the goal of systematically elucidating how genome architecture contributes to cancer development and informs precision diagnosis and therapy. As first or corresponding author (including co-first/co-corresponding), she has published in leading journals such as Cancer Discovery (2022), Nature Communications (2024a, 2024b), Genome Medicine (2024), Cancer Letters (2024), and Journal of Clinical Investigation (2020). Her work has received over 1,400 citations with an H-index of 12, including two ESI Highly Cited Papers. In addition, methods developed from her research have been granted one Chinese invention patent.
Overview of the research
Educational experience
Work experience
Representative achievements and articles


Jiapei Yuan is a Research Fellow and Tenure-Track Assistant Professor at Peking Union Medical College. Her research focuses on 3D genomics and precision oncology, with the goal of systematically elucidating how genome architecture contributes to cancer development and informs precision diagnosis and therapy. As first or corresponding author (including co-first/co-corresponding), she has published in leading journals such as Cancer Discovery (2022), Nature Communications (2024a, 2024b), Genome Medicine (2024), Cancer Letters (2024), and Journal of Clinical Investigation (2020). Her work has received over 1,400 citations with an H-index of 12, including two ESI Highly Cited Papers. In addition, methods developed from her research have been granted one Chinese invention patent.


Ph.D., Bioinformatics, Tsinghua University, China, 2012-2017

B.S., Biology, Shandong University, Jinan, China, 2008-2012

Assistant Professor, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 2023-

Associate Researcher, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 2021-2022

Postdoc researcher, Department of Pathology, UT Southwestern medical center, 2017-2020

MAJOR NATIONAL LEADERSHIP POSITIONS, SOCIETIES AND BOARDS:

2024-2027    Member, Committee of Tianjin Biomedical Engineering Society


SELECTED PUBLICATIONS:

1. Yuan J, et al. Prostate cancer transcriptomic regulation by the interplay of germline risk alleles, somatic mutations and 3D-genomic architecture. Cancer Discovery, 2022, Dec 2;12(12):2838-2855.

2. Yuan J#, Tong Y#, et al. A compendium of genetic variations associated with promoter usage across 49 human tissues. Nature Communications, 2024 Oct 9;15(1):8758.

3. Yuan J#*, Zhang J#, et al. Single-cell transcriptomic analysis of the immune microenvironment in pediatric acute leukemia. Cancer Letters, 2024 Jun 4:217018.