Tracing Haematopoietic Stem Cell Formation at Single-cell Resolution.


2016 May 18;533(7604):487-92. DOI: 10.1038/nature17997

Symptomatic Profiles of Patients With Polycythemia Vera:Implications of Inadequately Controlled Disease.

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Leukemia cell infiltration causes defective erythropoiesis partially through MIP-1α/CCL3.


2016 Sep;30(9):1897-908.

Loss of Dnmt3b accelerates MLL-AF9 leukemia progression.


2016 May 2. doi: 10.1038/leu.2016.112.

Novel regulators in hematopoietic stem cells can be revealed by a functional approach under leukemic condition.


2016 Oct;30(10):2074-2077.

Distinct molecular abnormalities underlie unique clinical features of essential thrombocythemia in children.


2016, 30(3):746-9

Rictor Plays a Pivotal Role in Maintaining Quiescence as well as Stemness of Leukemia Stem Cells in MLL-Driven Leukemia.


2016. Aug. 8th. DOI: 10.1038/leu.2016.223.

The catalytic activity of TET2 is essential for its myeloid malignancy-suppressive function in hematopoietic stem/progenitor cells.


2016. Mar. 8, doi: 10.1038/leu.2016.56.

Epigenetic silencing of miR-137 induces drug resistance and chromosomal instability by targeting AURKA in multiple myeloma.


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Thrombopoietin receptor agonists shift the balance of Fcγ receptors towards inhibitory receptor IIb on monocytes in ITP.


2016 Aug 11;128(6):852-61.

Osteoclasts promote immune suppressive microenvironment in multiple myeloma: therapeutic implication.


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Intratumoral genetic heterogeneity and number of cytogenetic aberrations provide additional prognostic significance in chronic lymphocytic leukemia.

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Enhanced Generation of Integration-free iPSCs from Human Adult Peripheral Blood Mononuclear Cells with an Optimal Combination of Episomal Vectors.

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Rheb1 promotes tumor progression through mTORC1 in MLL-AF9-initiated murine acute myeloid leukemia.

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Microarray-based analysis and clinical validation identify ubiquitin-conjugating enzyme E2E1 (UBE2E1) as a prognostic factor in acute myeloid leukemia.

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Antifungal prophylaxis of patients undergoing allogenetic hematopoietic stem cell transplantation in China: a multicenter prospective observational study.

J Hematol Oncol.

2016 Sep 23;9(1): 97.

Chasing the precursor of functional hematopoietic stem cells at the single cell levels in mouse embryos.

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2016 Jul 22;9(1):58.

Alantolactone selectively ablates acute myeloid leukemia stem and progenitor cells.

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2016 Sep 22;9(1):93.

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Rac1 GTPase promotes interaction of hematopoietic stem/progenitor cell with niche and participates in leukemia initiation and maintenance in mouse.

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Multicentre, randomised phase III study of the efficacy andsafety of eltrombopag in Chinese patients with chronicimmune thrombocytopenia.

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2016 Oct 13. doi: 10.1111/bjh.14380.

Validation of the WHO 2016 proposals for Myelodysplastic syndromes patients with the presence of ring sideroblasts but without excess blasts.

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ASXL1 plays an important role in erythropoiesis

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Bone Marrow Is a Reservoir for Cardiac Resident Stem Cells.

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Biochemical Pharmacology.

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A molecular pathology method for sequential fluorescence in situ hybridization for multi-gene analysis at the single-cell level.


2016 Jun 23.doi: 10.18632/oncotarget.10245.

Construction of a new anti-CD19 chimeric antigen receptor and the anti-leukemia function study of the transduced T cells


2016, 7(9):10638-49

Multiplex ligation-dependent probe amplification assay identifies additional copy number changes compared with R-band karyotype and provide more accuracy prognostic information in myelodysplastic syndromes.


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Colony-forming unit cell (CFU-C) assays at diagnosis: CFU-G/M cluster predicts overall survival in myelodysplastic syndrome patients independently of IPSS-R.


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Elevated neutrophil-to-lymphocyte ratio and monocyte-to-lymphocyte ratio and decreased platelet-to-lymphocyte ratio are associated with poor prognosis in multiple myeloma.


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2016 Apr 12;7(15):19589-600.

Mutations or copy number losses of CD58 and TP53 genes in diffuse large B cell lymphoma are independent unfavorable prognostic factors.


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E1A-engineered human umbilical cord mesenchymal stem cells as carriers and amplifiers for adenovirus suppress hepatocarcinoma in mice  


2016 Aug 9;7(32): 51815-51828.

The different prognostic impact of type-1 or type-1 like and type-2 or type-2 like CALR mutations in patients with primary myelofibrosis.

Am J Hematol.

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Heterogeneity of proangiogenic features in mesenchymal stem cells derived from bone marrow, adipose tissue, umbilical cord, and placenta.

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2016 Nov 10;7(1):163.

VCAM-1+ placenta chorionic villi-derived mesenchymal stem cells display potent pro-angiogenic activity.

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Reprogramming of Notch1-induced acute lymphoblastic leukemia cells into pluripotent stem cells in mice.

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Bone marrow fibrosis grade is an independent risk factor for overall survival in patients with primary myelofibrosis.

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Integrated Biophysical and Biochemical Signals Augment Megakaryopoiesis and Thrombopoiesis in a Three-Dimensional Rotary Culture System.

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Mesenchymal Stem Cells Derived from Human Bone Marrow and Adipose Tissue Maintain Their Immunosuppressive Properties After Chondrogenic Differentiation: Role of HLA-G.

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StemCellCKB: An Integrated Stem Cell-Specific Chemogenomics KnowledgeBase for Target Identification and Systems-Pharmacology Research.

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Mol Immunol.

2016 Oct;78:89-97.

'Waterloo': when normal blood cells meet leukemia.

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Prediction of adeno-associated virus neutralizing antibody activity for clinical application.

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Stromal cell-derived factor-1 rs2297630 polymorphism associated with platelet production and treatment response in Chinese patients with chronic immune thrombocytopenia.


2016 Jun;27(4):338-43. (IF: 2.982)

The polymorphisms of tumor necrosis factor-induced protein 3 gene may contribute to the susceptibility of chronic primary immune thrombocytopenia in Chinese population.


2016, 27(1):26-31 (IF: 2.982)

Impaired Autophagy in Adult Bone Marrow CD34+ Cells of Patients with Aplastic Anemia: Possible Pathogenic Significance.

PLoS One.

2016 Mar 1; 11(3):e0149586.

PD-1 Antibody Monotherapy for Malignant Melanoma: A Systematic Review and Meta-Analysis.

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2016 Aug 2;11(8): e0160485.

Clinical profile of megaloblastic anemia in China: a single center experience from MegA-1710 program over two decades.

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2016 Apr; 95(5):827-8.

SIRT2 mediates multidrug resistance in acute myelogenous leukemia cells via ERK1/2 signaling pathway.

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2016; 48(2): 613-623.

Persistent elevated bone marrow plasma levels of thrombopoietin in patients with aplastic anemia.


2016 Jun 3; 85:11-13.

Effects of the multidrug resistance-1 gene on drug resistance in primary immune thrombocytopenia.



Aberrant expression of long noncoding RNA TMEVPG1 in patients with primary immune thrombocytopenia



Different dosages of intravenous immunoglobulin (IVIg) in treating immune thrombocytopenia with long-term follow-up of three years: Results of a prospective study including 167 cases.


2016 Feb;49(1):50-7  (IF: 2.714)

Abnormal lipid rafts related ganglioside expression and signaling in T lymphocytes in immune thrombocytopenia patients.


2016 Feb;49(1):58-68(IF: 2.714)

Tri-allelic patterns at the D7S820 locus detected in twogenerations of a Chinese family.,

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Transcriptome AnalysisReveals a Ribosome Constituents Disorder Involved in the RPL5 DownregulatedZebrafish Model of Diamond-Blackfan Anemia.

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2016 Mar 9;9(1):13. doi: 10.1186/s12920-016-0174-9.

Identification of mutations in the F8 and F9 gene in families with haemophilia using targeted high-throughput sequencing.


2016 Sep;22(5):e427-34.

Chinese HERO study group. The demographics, treatment characteristics and quality of life of adult people with haemophilia in China - results from the HERO study.


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2016 Oct 18. doi: 10.1111/ejh.12821.

Decreased expression of vitamin D receptor may contribute to the hyperimmune status of patients with acquired aplastic anemia.

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2016 May; 96(5):507-16.

Role of vitamin D receptor gene polymorphisms in aplastic anemia: a case-control study from China.

Int J Lab Hematol.

2016 Jun; 38(3):273-83.

A novel lymphoid progenitor cell population (LSKlow) is restricted by p18INK4c.

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A new HLA-B allele, B*52:44, sequenced in a Chinese individual.


2016 Jun;87(6):464-5.

Identi_cation of a novel HLA-C06variant allele HLA-C06166 by sequence-based typing ina Chineseindividual


2016 Dec;88(6):315-316.

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2016 May;103(5):487-97.

mTORC Signaling in Hematopoiesis.

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Clinical features, mutations and treatment of 104 patients of Diamond-Blackfan anemia in China: a single-center retrospective study.

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2016 Oct;104(4):430-9.

Novel chemical attempts at ex vivo hematopoietic stem cell expansion.

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2016 May;103(5):519-29. doi: 10.1007/s12185-016-1962-x. Review.PMID:26910241(综述)

Interferon‑γ alters the microRNA profile of umbilical cord‑derived mesenchymal stem cells.

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2016 Nov;14(5):4187-4197.

Nutritional status survey of aplastic anemia patients - a single center experience in China.

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2016 May; 30:142-7.

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TET2 mutations were predictive of inferior prognosis in the presence of ASXL1 mutations in patients with chronic myelomonocytic leukemia.

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A systematic classification of megakaryocytic dysplasia and its impact on prognosis for patients with myelodysplastic syndromes.

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Mesenchymal stem cells: Immunomodulatory capability and clinical potential in immune diseases.

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Impact of Autologous Mesenchymal Stem Cell Infusion on NeuromyelitisOptica Spectrum Disorder: A Pilot, 2-Year Observational Study. CNS


2016 Aug;22(8):677-85.带名

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Fluorescence In situ Hybridization: Cell-Based Genetic Diagnostic and Research Applications.

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