2002.09—2006.07  哈尔滨工业大学，学士
2006.09—2009.06  南开大学，硕士
2010.09—2013.06  北京协和医学院、博士

2013.08--2017.09  中国医学科学院血液病医院，助理研究员

2017.09--2018.02  中国医学科学院血液病医院，副研究员

2018.02--2018.07  美国圣裘德儿童医院访问学者

2018.07--2023.01  中国医学科学院血液病医院，副研究员

2023.01—至今      北京协和医学院，准长聘系列助理教授                                       

                           中国医学科学院血液病医院血液与健康全国重点实验室，研究员

1. 中国医学科学院医学与健康科技创新工程科技攻关专项项目，2025-I2M-KJ-027，RAS 突变驱动的儿童髓系肿瘤发病机制和干预策略研究，2025-07至2027-06，270万元，在研，课题负责人

2. 中国医学科学院医学与健康科技创新工程科技人才支持专项，2025-I2M-XHJC-040，儿童白血病的耐药复发机制与临床转化研究，2025年11月1日至2028年10月31日，300万元，在研，课题负责人

3. 科技部，国家重点研发计划“干细胞研究与器官修复”，2021YFA1101603，用于特定适应症治疗的间充质干细胞药物有效性分子标志物的研究，2021-12至2026-06，396万元，结题，课题负责人

4. 中国医学科学院中央级公益性科研院所基本科研业务费青年医学人才奖励项目，2018RC310019,利用CRISPR/Cas9文库筛选技术和多组学测序 技术探索儿童急性髓系白血病复发耐药机制，2018.10-2019.09，50万元，结题，主持

5. 国家自然科学基金面上，81770175，PDGFRB重排协同IKZF1突变在Ph-like ALL发生及耐药中作用机制的研究, 2018.01-2021.12, 53万元，结题，主持

6. 国家自然科学基金青年项目，81400137，组蛋白甲基化复合物PRC2在ETP T-ALL中作用的研究，2015/01-2017/12，23万元，结题，主持

1. Jiarui Zheng, Linlin Jin, Yunlong Chen, Yongjuan Duan, Suyu Zong, Peng Wu, Xiaofan Zhu, Wenyu Yang*, Tianyuan Hu*, Yingchi Zhang*. Targeting p16INK4a-mediated cellular senescence as a therapeutic strategy for FLT3-ITD-driven acute myeloid leukemia. Leukemia. 2025 Nov;39(11): 2652-2662.

2. Jingliao Zhang#*, Yongjuan Duan#, Peng Wu#, Yanxia Chang#, Yue Wang, Tianyuan Hu, Chao Liu, Xiaoyan Chen, Suyu Zong, Xiaoli Chen, Yangping Wu, Linlin Jin, Yang Lan, Xiaoming Liu, Xuelian Cheng, Feng Ding, Tianyu Li, Xiaojuan Chen, Ye Guo, Yumei Chen, Wenyu Yang, Li Zhang, Yao Zou, Tao Cheng, Xiao-Fan Zhu*, Yingchi Zhang*. Clonal evolution dissection reveals high MSI2 level promotes chemo-resistance in T-cell acute lymphoblastic leukemia. Blood. 2024 Jan 25;143(4):320-335.

3. Yaojin Huang#, Xiaowei Xie#, Mengyao Liu#, Yawen Zhang#, Junye Yang, Wenling Yang , Yu Hu, Saibing Qi, Yahui Feng, Guojun Liu, Shihong Lu, Xuemei Peng, Jinhui Ye, Shihui Ma, Jiali Sun, Lu Wang, Linping Hu, Lin Wang, Xiaofan Zhu, Hui Cheng, Zimin Sun, Junren Chen, Fang Dong*, Yingchi Zhang*, Tao Cheng*. Restoring mitochondrial function promotes hematopoietic reconstitution from cord blood following cryopreservation-related functional decline. J Clin Invest. 2025 Mar 4;135(9):e183607.

4. Jiapei Yuan*, Jingliao Zhang*, Beibei Zhao, Fang Liu, Tianfeng Liu, Yongjuan Duan, Yumei Chen, Xiaojuan Chen, Yao Zou, Li Zhang, Ye Guo, Wenyu Yang, Yang Yang, Jun Wei#, Xiaofan Zhu#, Yingchi Zhang#. Single-cell transcriptomic analysis of the immune microenvironment in pediatric acute leukemia. Cancer Letters, 2024 Aug 1:596:217018.

5. Jingliao Zhang#, Tianfeng Liu#, Yongjuan Duan#, Yanxia Chang#, Lixian Chang, Chao Liu, Xiaoyan Chen, Xuelian Cheng, Tianyu Li, Wenyu Yang, Xiaojuan Chen, Ye Guo, Yumei Chen, Yao Zou, Li Zhang, XiaofanZhu*, Yingchi Zhang*. Single-cell analysis highlights a population of Th17-polarized CD4+ naïve T cells showing IL6/JAK3/STAT3 activation in pediatric severe aplastic anemia. J Autoimmun. 2023 Apr:136:103026.

6. Yingchi Zhang#, Shicheng Wang#, Jingliao Zhang#, Chao Liu#, Xinqi Li, Wenbo Guo, Yongjuan Duan, Xiaoyan Chen, Suyu Zong, Jiarui Zheng, Yixuan W u, Xiaoli Chen, Xuelian Cheng, Yanxia Chang, Yue Wang, Feng Ding, Wenyu Yang, Xiaojuan Chen, Ye Guo, Li Zhang, Yumei Chen, Yao Zou, Xiaofan Zhu*, Jin Gu*, Tao Cheng*. Elucidating Minimal Residual Disease of Pediatric B cell Acute Lymphoblastic leukemia by Single Cell Analysis. Nature Cell Biology, 2022 Feb;24(2):242-252.

7. Riguo Fang#, Jingliao Zhang#, Huihui Yang, Jia Shi, Huimin Zeng, Xiaofan Zhu, Dong Wei, Pengfei Yuan, Tao Cheng*, Yingchi Zhang*. Highly efficient gene editing and single cell analysis of hematopoietic stem/progenitor cells from X-linked sideroblastic anemia patients. Signal Transduct Target Ther. 2021 Jul 2;6(1):248.

7. Jingliao Zhang#, Yingchi Zhang#*, Man Zhang, Chao Liu, Xiaoming Liu, Jie Yin, Peng Wu, Xiaojuan Chen, Wenyu Yang, Li Zhang, Ye Guo, Yao Zou, Yumei Chen, Youjia Cao, Tao Cheng*, Xiaofan Zhu*. FLT3 pathway is a potential therapeutic target for PRC2 mutated T cell acute lymphoblastic leukemia. Blood. 2018 Dec 6;132(23):2520-2524.

8. Yingchi Zhang#, Yufeng Gao#, Hui Zhang#, Jingliao Zhang, Fuhong He, Aleš Hnízda, Maoxiang Qian, Xiaoming Liu, Yoshihiro Gocho, Ching-Hon Pui, Tao Cheng, Qianfei Wang, Jun J. Yang*, Xiaofan Zhu*, Xin Liu*. PDGFRB mutation and tyrosine kinase inhibitor resistance in Ph-like acute lymphoblastic leukemia. Blood. 2018 May 17;131(20):2256-2261.

9. Yingchi Zhang#, Jingliao Zhang#, Wenbin An#, Yang Wan, Shihui Ma, Jie Yin, Xichuan Li, Jie Gao, Weiping Yuan, Ye Guo, James Douglas Engel, Lihong Shi*, Tao Cheng*, Xiaofan Zhu*. Intron 1 GATA site enhances ALAS2 expression indispensably during erythroid differentiation. Nucleic Acids Res. 2017 Jan 25;45(2):657-671.